Abstract Predictive factors for response to regorafenib in recurrent glioblastoma, IDH-wildtype, are scarcely recognized.The objective of this study was to identify molecular predictive factors for response to regorafenib using a clinically available platform.We analyzed a prospective cohort of 30 patients harboring recurrent glioblastoma, IDH-wild
A new method for positioning mini-implants in orthodontic patients with tooth position anomalies (ICD-10 K07.3) using a navigation surgical template is proposed.The template is APP CONTROLLED used to position a mini-implant precisely based on the visualization results of cone beam computed tomography (CBCT), which facilitates safe and dynamic ortho
The human YB-1 protein plays multiple cellular roles, of which many are dictated by its binding to RNA and DNA through its Cold Shock Domain (CSD).Using molecular dynamics simulation approaches validated by experimental assays, the YB1 CSD was found to interact Knee Protection with nucleic acids in a sequence-dependent manner and with a higher affi
Detecting imaging artifacts is a precondition for interpreting seismic profiles, as well as one of the fidelity (accuracy) measures for all seismic images.Based on return field seismic reflection profiles, this paper analyzes some common and often miss-interpreted seismic imaging artifacts, and proposes to detect the artifacts through analyzing the